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ʻO ka pauma Olivetol (500-66-3)

ʻO Olivetol kahi pūlea kūlohelohe kūlohelohe. Loaʻa ʻia ma kekahi mau ʻano o nā lichens a hiki ke kiʻi ʻia koke. ʻO 5-Pentylresorcinol i hua ʻia e ka nui o nā mea hihiu, ai ʻole he pheromone, he mea hele a he antiseptic paha. Hoʻokomo ʻia ka mea kanu cannabis i nā mea pili i ka waikawa olivetolic acid (OLA), a ua hypothesized ʻo ka mea kanu e hoʻohuli ai i ka biosynthesize o ka huahana tetrahydrocannabinol (psychoactive tetrahydrocannabinol).

Hana: Hana Hana
pūʻolo: 1KG / ʻeke, 25KG / pahu
Hiki i ka Wisepowder ke hana a hāʻawi i ka nui. ʻO nā hana a pau ma lalo o ke kūlana cGMP a me ka ʻōnaehana hoʻomalu maikaʻi koʻikoʻi, loaʻa nā palapala hoʻāʻo a pau.

ʻO ka wikiō Olivetol (500-66-3) wikiō

 

 

Olivetol pauka (500-66-3) Pūnaewele ʻike

inoa Olivetol (3,5-hydroxypentylbenzene) pauka
CAS 500-66-3
Purity 98%
Inoa inoa inoa ʻO Olivetol
'O Synonyms 3,5-Dihydroxyamilbenzene; 5-n-Amylresorcinol; 5-n-Pentylresorcinol; 1,3-Dihydroxy-5-pentylbenzene; 5-Pentyl-1,3-benzenediol;
Ka Lā Molecular C11H16O2
Molecular Weight 180.2435
Point Hoʻolālā 46-48 ° C (kahi.).
InChI Key IRMPFYJSHJGOPE-UHFFFAOYSA-N
ano paa
Keʻano māmā aʻalani paha i ka aniani kala
Half Ole /
Palekana Māleʻa ka wai i loko o ka wai (mahele hapa i ʻole), chloroform, a me ka methanol.
pūnaewele Kūlana: I loko o kahi hale mālama malo a maloʻo; haʻalele i ka mahana; pale i ke ahi; pale i ka humu.
noi Olivetol i biosynthesized e kahi polyketide synthase-type type mai hexanoyl-CoA a meʻākolu mololi o malonyl-CoA e kahi aldol kuʻuna o kahi tetraketide waena.
Hōʻike hōʻike palapala Available

 

ʻO ka oliva Olivetol (500-66-3) ʻO ka wehewehe nui

Ua hoʻohana ʻia ʻo Olivetol ma ke ʻano he molekula laʻa ma ke kāpili ʻana o ka molelika polika (MIP). Ua hoʻohana pū ʻia ʻo ia ka mea pale o (S) -mephenytoin 4′-hydroxylase i ka hana o ka mea hoʻohui CYP2C19.

Hoʻohana ʻia ka Olivetol i loko o nā ʻano hana like ʻole e hana i nā mea hoʻohālike synthetic o THC.full citation e pono ai: ʻO kekahi ʻano hana e like me ka uka o ka lāʻau o ka olivetol a me ka pulegone. I PiHKAL, ua hōʻike ʻo Alexander Shulgin i kahi ʻano cruder e hana ana i ka huahana like ma o ka lawe ʻana i ka hopena olakol a me nā aʻa hinu pono o ka ʻoni i mua o ka phosphoryl chloride.

ʻO kahi ala no ka hoʻohuihui ʻana o THC pono pū kekahi o ke ʻano condens ma waena o olivetol a me Δ2-carene oxide

 

ʻO ka mōlī Olivetol (500-66-3) ʻO ka mōʻaukala

Hoʻokomo ʻia ʻo Olivetol e kahi polyketide synthase-ʻano ʻano mai hexanoyl-CoA a ʻekolu mau mole o malonyl-CoA e kahi condo aldol o kahi waena tetraketide. I ka makahiki 2009, Taura et al. ua hiki ke kālani i kahi ʻano III PKS i kapa ʻia ʻo olivetol synthase (OLS) mai Cannabis sativa. ʻO kēia PKS kahi protein homodimeric i loko o kahi 385 amino acid polypeptide me kahi mole mole o 42,585 Da nona ke ʻano like kiʻekiʻe (60-70%) ʻike e kanu ai iā PKS.

 

Olivetol powder (500-66-3) Ke lawelawe

1, hoʻohana ʻia i ka ʻoihana lāʻau lapaʻau.

2, hoʻohana ʻia ma waena o Organic Intermediate.

3, Hoʻohana ʻia e like me ka manaʻo o ka lipopolysaccharides, carrageenan a me ka sialic acid.

 

Olivetol pauma (500-66-3) ʻOi aku ka nui o ka noiʻi

ʻO ka hana ʻana, hoʻoili ai, a i ʻole e hoʻohele ʻia ʻana i ka oliva ʻaʻole i kolohe ʻia e kekahi ʻāina; Eia nō naʻe, i ka ʻAmelika Hui Pū ʻIa, he DEA i nānā mua i mua.

 

ʻO ka pauma Olivetol (500-66-3) Hōʻailona

  • Kumano, T., et al. Bioorg. Med. Chem., 16, 8117 (2008), Appendino, G., et al .: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., et al .: Food Chem., 115, 1170 (2009),
  • . ^ E Ha yM. Jiang R, et al. ʻO Cannabidiol kahi mea hoʻomehana paʻa o ka hana catalytic o ka cytochrome P450 2C19. Kauka Metab Pharmacokinet. 2013; 28 (4): 332-8.
  • . ^ E Ha yM. Yamaori S, et al. ʻO Cannabidiol, kahi phytocannabinoid koʻikoʻi, ma ke ʻano o kahi mea ākea atypical inhibitor no CYP2D6. Hoʻopaʻa i ka lāʻau Metab. 2011 Nov; 39 (11): 2049-56.

 

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