Products

Pauda Fisetin (528-48-3)

ʻO Fisetin kahi polyphenol botanical maʻamau a me flavonoid i loaʻa i nā ʻano mea kanu like ʻole, nā huaʻai a me nā mea kanu e like me nā strawberry, nā ʻāpala, nā persimmons, nā ʻaka a me nā kukama. Ua manaʻo ʻia ʻo Fisetin kahi pigment mea kanu e hāʻawi ana i nā hua a me nā mea kanu, e like me nā strawberry, me ko lākou kala a me nā hiʻohiʻona. Loaʻa i ka Fisetin kahi ʻano like mole e like me ka flavonoid mea kanu ʻoi aku ka makemake a me Quercetin. ʻAʻole like iā Quercetin, akā, he senolitik paha ʻo Fisetin a malia paha ʻo kekahi o nā senolytic mana loa i ʻike ʻia.

Hana: Hana Hana

pūʻolo: 1KG / ʻeke, 25KG / pahu

Hiki i ka Wisepowder ke hana a hāʻawi i ka nui. ʻO nā hana a pau ma lalo o ke kūlana cGMP a me ka ʻōnaehana hoʻomalu maikaʻi koʻikoʻi, loaʻa nā palapala hoʻāʻo a pau.

Ke noi aku i kahi mea noi

Māhele: ʻO ka maʻi o Alzheimer

1. He aha ka Fisetin?

2. The Mechanism Of Action of Fisetin: Pehea ka hana o Fisetin?

3. He aha ka meaʻai i loaʻa iā Fisetin?

4. He aha nā pōmaikaʻi o Fisetin?

5.Fisetin Vs Quercetin: ua like anei ka fisetin me ka quercetin?

6.Fisetin Vs Resveratrol: ʻoi aku ka maikaʻi o ka fisetin ma mua o ka resveratrol?

7.Fisetin a me ke kaumaha

8. ʻEhia ka nui o ka fisetin e pono iaʻu e lawe: ʻO ka dosage fisetin?

9. He aha nā hopena o ka fisetin?

10.Fisetin pauka a me fisetin mea hoʻopihapiha ma ka pūnaewele

Fisetin Chemical Base Information Kaʻike Base

inoa	Pauka Fisetin
CAS	528-48-3
Purity	65% ， 98%
Inoa inoa inoa	2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
'O Synonyms	2- (3,4-dihydroxyphenyl) -3,7-dihydroxychromen-4-one, 3,3 ", 4", 7-Tetrahydroxyflavone, 5-Deoxyquercetin, Natural Brown 1, CI-75620, NSC 407010, NSC 656275, BRN 0292829, Cotinin, 528-48-3 (anhydrous)
Ka Lā Molecular	C15H10O6
Molecular Weight	286.24
Point Hoʻolālā	330 ° C (dec.)
InChI Key	GYHFUROKCOMWNQ-UHFFFAOYSA-N
ano	paa
Keʻano	ʻ .lelo kikowaena
Half Ole	/
Palekana	100 mM hiki i ka DMSO a me ka 10 mM ma ka anhanol
pūnaewele Kūlana:	−20 ° C no ka manawa lōʻihi
noi	ʻO Fisetin kahi sirtuin ikaika e hoʻouluulu nei i ka hui (STAC), antiinflam inflammatory a me ka mea anticancer agents
Hōʻike hōʻike palapala	Available

Hoʻohana pinepine ʻia nā flavonoid polyphenols no kā lākou waiwai antioxidant. ʻO kā lākou kumu nui nā huaʻai a me nā mea kanu e ʻai mau ʻia, e nā miliona o ka honua. Ma muli o ko lākou mau pono olakino, ua lilo nā flavonoids i mea nui i nā mea hoʻohui meaʻai like ʻole, ʻoi aku ka resveratrol. Ua loaʻa i nā haʻawina hou he flavonoids hou ʻo ia ka fisetin, i manaʻo ʻia ʻo ia ka mea ikaika loa ma waena o nā flavonoids ʻē aʻe i hoʻohana ʻia ma ke ʻano he meaʻai. ʻO ka pauka Fisetin a i ʻole nā mea hoʻohui Fisetin ua hoʻonui ʻia i ka noi ma muli o kā lākou pono olakino.

He aha ka Fisetin?

ʻO Fisetin kahi polyphenol flavonoid e hana ana ma ke ʻano he puaʻa melemele i nā mea kanu. ʻIke mua ʻia i ka makahiki 1891, loaʻa ka fisetin i nā huaʻai a me nā mea kanu like me ka persimmon a me nā strawberries. ʻOiai ua lōʻihi ia, ʻo ia wale nō ka mea i ʻike ʻia nā pōmaikaʻi fisetin a hoʻohālikelike ʻia me nā mea hoʻohui ʻē aʻe. Eia kekahi, ʻo ia nā pono lapaʻau kūpono o ka pauka fisetin i paipai i ka noiʻi ʻana i ke kumuhana. ʻOiai ua aʻo ʻia a ua ʻike ʻia nā pono fisetic a me nā hopena ʻaoʻao fisetin, aia nō ka nui o nā mea ʻepekema i hiki ʻole ke hoʻomaopopo e pili ana i ka flavonoids.

ʻO ka Mechanism of Action of Fisetin: Pehea e hana ai ʻo Fisetin?

Hana ka pauka Fisetin ma nā ala he nui i loko o ke kino kanaka. Hana nui ʻo Fisetin i nā pae antioxidants i ke kino a ʻo ia kekahi o kāna mau pono nui. E hakakā ana i nā radical manuahi, he mau ion paʻa ʻole e komo i nā hopena kemika ʻino e hōʻino i ke kino. ʻO nā waiwai antioxidant o Fisetin e ʻae iā ia e hoʻokaʻawale i kēia mau radical manuahi a no laila, e hōʻemi i ke koʻikoʻi oxidative i lalo o ke kino.

ʻO kekahi hana ʻē aʻe o ka fisetin ʻo ia ka pale ʻana i ke ala NF-KB. He mea nui kēia ala no ka hana ʻana a me ka hoʻokuʻu ʻana i nā cytokine pro-inflammatory a ma hope, ʻeha. ʻO NF-KB kahi ala pro-inflammatory e hoʻoulu ai i ka transcription gene e synthesize i nā protein inflammatory. Ke hoʻoikaika nui ʻia, he kuleana koʻikoʻi ke ala NF-KB i ka hoʻomohala ʻana i ka maʻi kanesa, nā allergies, a me nā maʻi autoimmune. Hoʻopili ka pauka Fisetin i kēia ala, no laila, e hana ana ma ke ʻano he anti-inflammatory supplement.

Hoʻopili pū ka pauka Fisetin i ka hana o ke ala mTOR. ʻO kēia ala, e like me ke ala NF-KB, pili i ka ulu ʻana o ka maʻi kanesa, ka maʻi diabetes, ka momona, a me nā maʻi neurodegenerative. ʻO ke ala mTOR ka mea e hopohopo ai nā cell i ko lākou hakakā ʻana e hoʻokō i nā koi o ka ikehu o ke ala, e hopena i ka hana ʻoi loa i nā cell. ʻO ke ʻano o ia mea, ke hana nui nei nā cell a hana i ka ʻōpala metabolic akā ʻaʻole lawa ka manawa e hoʻomaʻemaʻe ai i ka ʻōpala i hopena i ka hōʻiliʻili ʻana o ka ʻōpala. Hiki ke hōʻino ʻia kēia i ke olakino kelepona a ʻo ka paʻa ʻana o kēia ala e ka fisetin supplement ke ʻano o ke kōkua ʻana o fisetin i ka mālama ʻana i ka momona, ka maʻi diabetes, a me ke kanesa.

Ma waho aʻe o kēia mau hana nui o ka hana, hiki i ka fisetin ke kāohi i ka hana o nā enzymes degrading lipid, lipoxygenases. Kāohi ia i ka matrix metalloproteinases a i ʻole ka ʻohana MMP o nā enzymes. He mea koʻikoʻi kēia mau enzymes no nā cell cancerous e hiki ai ke hoʻouka i nā ʻiʻo ʻē aʻe, akā naʻe, me ka hoʻohana ʻana i ka pauka fisetin, ʻaʻole hiki ke hiki.

He aha ka meaʻai i loaʻa iā Fisetin?

ʻO Fisetin kahi flavone i hoʻokumu ʻia i nā mea kanu i lawe mua ʻia mai nā ʻāpala a me nā strawberries. He puaʻa melemele a me ka kala ʻoker i nā mea kanu, ʻo ia hoʻi, ʻo ka hapa nui o nā huaʻai a me nā mea kanu o ia kala he waiwai i ka fisetin. ʻO Fisetin, i nā mea kanu, ua synthesized mai ka amino acid phenylalanine, a ʻo ka hōʻiliʻili ʻana o kēia flavone i nā mea kanu e hilinaʻi nui ʻia i ke kaiapuni o ka mea kanu. Inā ʻike ʻia ka mea kanu i nā nalu pōkole o nā kukuna UV, a laila hoʻonui ka hana o fisetin. Hana ʻia ka pauka Fisetin mai ka hoʻokaʻawale ʻana o fisetin mai nā kumu mea kanu.

Kumuwaiwai kanu	Ka nui o Fisetin (μg /g)
ʻO Toxicodendron vernicifluum	15000
Strawberry	160
Apple	26
Persimmon	10.6
Onion	4.8
Aʻa Lotus	5.8
ʻO ka hua waina	3.9
Kiwifruit	2.0
Peach	0.6
Kūkamo	0.1
ʻO Tomato	0.1

He aha nā pōmaikaʻi o Fisetin?

He liʻiliʻi nā pōmaikaʻi Fisetin, a ua ʻike ʻia lākou āpau ma nā ʻano holoholona. ʻAʻohe noiʻi i hiki ke hoʻoholo paʻa i kēia mau pōmaikaʻi i loko o ke kanaka no ka mea ʻo ka hapa nui o nā haʻawina aia nō i ka pae lapaʻau. ʻO nā pono like ʻole o fisetin e komo pū:

Anati-kūnewa

Hōʻike ʻia ka ʻelemakule o ke kino e ka piʻi ʻana o nā cell senescent, ʻaʻole hiki ke hoʻokaʻawale. Hoʻokuʻu kēia mau pūnaewele i nā hōʻailona inflammatory, kahi i hopena i nā pilikia o ka ʻelemakule i ʻike pinepine ʻia. ʻO ka hapa nui o nā maʻi e pili ana i ka makahiki ma muli o ka ʻaʻa ʻino i loko o ke kino i hoʻoikaika ʻia e nā cell senescent. ʻO ka hoʻohana ʻana i ka pauka Fisetin e kuhikuhi i kēia mau cell a hoʻoneʻe iā lākou mai ke kino, no laila, e hōʻemi ana i ka mumū a hoʻolohi i ke kaʻina hana ʻelemakule.

Ka mālama diabetes

I nā ʻano holoholona, ua hōʻike ʻia ka hoʻohui fisetin e hoʻemi nui i ke kō koko koko. Loaʻa kēia hopena o ka fisetin mai ka hiki o ka flavonoid ke hoʻonui i ka pae o ka insulin, hoʻonui i ka synthesis glycogen, a hoʻemi i ka hiki o ke ake ke hoʻomaka i ka gluconeogenesis. ʻO ke kumu, hana ʻo fisetin i kēlā me kēia ala i loko o ke kino e hopena i ka hana glucose a hoʻōki i kēlā me ka hoʻāla ʻana i nā ala e mālama ai a hoʻohana paha i ka glucose i ke kahe koko.

Anti-maʻi maʻi

ʻOkoʻa nā hopena anti-cancer o ka pauka fisetin ma muli o ke ʻano o ka maʻi kanesa. Ma kahi noiʻi i hana ʻia ma ka maʻi maʻi prostate, hiki i ka fisetin ke hōʻemi i ka ulu ʻana o ka maʻi kanesa ma ke kāohi ʻana i ka testosterone a me DHT receptors, he mea nui ia no ka ulu ʻana o ka maʻi maʻi prostate. Ma kahi noiʻi ʻē aʻe kahi i aʻo ʻia ai ka maʻi kanesa ʻo ia ka maʻi maʻi ʻaʻai, hiki i nā mea hoʻohui fisetin ke hoʻonui i nā antioxidants i loko o ke koko i hoʻemi ʻia e ka hoʻohana ʻana i ka paka. Ua hiki nō iā Fisetin ke hoʻemi i ka ulu ʻana o ka maʻi maʻi maʻi maʻi e 67 pakeneka ma kāna iho, a he 92 pakeneka ke hui pū ʻia me kahi lāʻau lapaʻau chemotherapy. Ke hoʻohana ʻia i ka maʻi maʻi ʻāʻī, ua hoʻemi nui ʻo fisetin i ka ʻāʻī e pili ana me ka maʻi maʻi ʻaʻai. ʻAʻole naʻe i haʻi ka haʻawina i kekahi hopena o ka fisetin i ka ulu ʻana o ka maʻi kanesa.

Neuroprotective

I ka wā i hāʻawi ʻia ai nā ʻiole kahiko me ka emi ʻana o ka makahiki i ka cognition, ua hoʻomaikaʻi maikaʻi ʻia ko lākou noʻonoʻo a me ka hoʻomanaʻo. Ma kahi noiʻi ʻē aʻe, ua hōʻike ʻia nā ʻano holoholona i nā mea neurotoxic a laila hāʻawi ʻia i kahi hoʻohui fisetin. Ua ʻike ʻia nā kumuhana hoʻāʻo ʻaʻole i ʻike i ka nalowale hoʻomanaʻo ma muli o ka hoʻohui. Eia naʻe, ʻaʻole i ʻike ʻia inā hiki i ka fisetin ke hele i ka pale koko-lolo kanaka me ka hana like me ka pale koko-lolo ʻiole.

ʻO Fisetin kekahi neuroprotective i ke ʻano e pale ai i ka ulu ʻana o nā maʻi neurodegenerative e like me Alzheimer ma ka hōʻemi ʻana i ka hōʻiliʻili ʻana o nā protein ʻino i loko o ka lolo. Pēlā nō, hōʻike ka ʻiole me ka ALS i ka hoʻomaikaʻi ʻana i ko lākou kaulike a me ka hoʻonohonoho ʻana o ka ʻiʻo ma hope o ka hāʻawi ʻia ʻana o ka pauka fisetin. Ua ʻike pū lākou i kahi ola lōʻihi ma mua o ka mea i manaʻo ʻia.

Cardioprotection

Ua aʻo ka poʻe noiʻi i ka hopena o ka pauka fisetin i ka pae cholesterol o nā ʻiole i hānai ʻia i ka meaʻai momona. Ua ʻike ʻia ua emi ka nui o ka cholesterol a me nā pae LDL akā ua aneane pālua ka pae HDL. Ua manaʻo ʻia ʻo ka hana hypothesized e hoʻokuʻu ai i ka cholesterol i loko o ka bile. ʻO ka cholesterol hōʻemi, holoʻokoʻa, he hopena cardioprotective.

ʻO kēia mau pōmaikaʻi fisetin āpau e kuhikuhi ana i ka anti-aging a me ka lōʻihi o ke ola e lawa ai ka hoʻolaha ʻana i nā noiʻi lapaʻau hou aʻe i hiki ke ʻae ʻia ka hui no ka hoʻohana lāʻau.

Fisetin Vs Quercetin: ua like anei ka fisetin me ka quercetin?

ʻO Quercetin a me Fisetin nā mea kanu flavonoids a i ʻole nā puaʻa i ʻike maikaʻi ʻia no kā lākou mau anti-inflammatory a me nā waiwai anti-oxidant. Loaʻa iā lāua ʻelua nā waiwai anti-ʻelemakule, a lākou e hana ai ma ka hoʻomaʻemaʻe ʻana i nā cell senescent mai ke kino. ʻO ka pauka Fisetin, akā naʻe, ua hōʻike ʻia e hoʻomaʻemaʻe i nā cell me ka hoʻonui ʻana i ka pono a me ka ikaika ma mua o ka quercetin.

Fisetin Vs Resveratrol: ʻoi aku ka maikaʻi o ka fisetin ma mua o ka resveratrol?

ʻO Resveratrol kahi polyphenol i kaulana loa no kāna mau waiwai anti-oxidant. ʻO ka lawe ʻana i ka quercetin a me ka resveratrol ka hopena i ka hopena synergistic i ke kino, ʻoiai ʻoi aku ka ikaika o ka quercetin i ka hoʻopili ʻana i ka mumū a me ka hoʻokele ʻana i ka insulin resistance. No ka mea ʻoi aku ka maikaʻi o Fisetin i ka hana ʻana i kēia mau hana ma mua o ka quercetin, hiki ke hoʻoholo ʻia ʻoi aku ka maikaʻi o ka fisetin supplement ma mua o ka quercetin. hoʻohui kaiihoʻi ʻana.

Fisetin a me ke kaumaha

Ua aʻo nā mea noiʻi i ka hopena o ka pauka fisetin i ka hōʻiliʻili momona i loko o ke kino a ua ʻike ʻia ua poloka ia i kekahi mau ala e hōʻemi ai i ka momona pili i ka meaʻai. Kuhi ia i ke ala hōʻailona mTORC1. He mea nui kēia ala no ka ulu ʻana o ka cell a me ka synthesis lipid, no laila, e hoʻoulu ai i ka momona i loko o ke kino.

ʻEhia ka nui o ka fisetin e pono iaʻu e lawe: ʻO ka dosage fisetin?

ʻO ka nui o ka lāʻau Fisetin ma waena o 2 mg a 5 mg, no ka kilo o ke kaumaha, akā naʻe, ʻaʻole kēia ke alakaʻi kuhikuhi no ka dosage. ʻAʻohe ʻōlelo aʻoaʻo kikoʻī no ka hoʻohana ʻana i ka fisetin, a ʻo ke kamaʻilio ʻana me ke kauka lapaʻau e kōkua i ka hoʻoholo ʻana i kahi pae hoʻohālikelike fisetin, kikoʻī i kona kūlana ponoʻī. Ma kekahi o nā haʻawina i hana ʻia me ke kumu o ka loiloi ʻana i ka hopena o ka pauka fisetin i ka mumū i hoʻokumu ʻia e ka maʻi maʻi colon, pono ʻo 100 mg i kēlā me kēia lā e ʻike i kahi hoʻohaʻahaʻa nui o ka mumū.

He aha nā hopena ʻaoʻao o ka fisetin?

Ua lilo ʻo Fisetin i kumuhana o nā noiʻi lehulehu a me nā ʻāpana noiʻi like ʻole. ʻO kēia hoihoi hope loa i ka flavonoids ʻo ia hoʻi, ʻo ka hapa nui o nā haʻawina i hana ʻia ma nā ʻano holoholona a i ʻole kahi hoʻonohonoho lab. ʻAʻole nui nā haʻawina kanaka i hana ʻia e hoʻoholo pono i nā hopena ʻaoʻao a me nā mea ʻona o ka hoʻohui. ʻAʻole i hōʻike ʻia nā hopena maikaʻi ʻole o nā holoholona holoholona i ka ʻike ʻana i ka nui o ka fisetin supplement, e kuhikuhi ana i ka palekana o ka mea hoʻohui.

Eia naʻe, he mea nui e hoʻomanaʻo i ka nele o nā hopena ʻaoʻao i nā hiʻohiʻona holoholona ʻaʻole ia he manaʻo ʻaʻole i loaʻa ka pilikia o nā hopena ʻaoʻao i loko o ke kanaka. No ka hiki ʻana i kēlā hopena, pono e hana ʻia nā haʻawina hauʻoli hou aku. I loko o kahi noiʻi i hana ʻia i nā maʻi maʻi maʻi e loiloi i ka pono o ka pauka fisetin i ka mālama ʻana i nā hōʻailona o ka maʻi kanesa, ua hōʻike ʻia nā placebo a me nā pūʻulu hoʻomalu i ka ʻeha o ka ʻōpū. Ma muli o ka loaʻa ʻana o ka hopena ʻaoʻao i nā pūʻulu ʻelua, a ke hana nei nā hui ʻelua i ka chemotherapy i ka manawa like, paʻakikī ke hoʻoholo i ka ʻai ʻana o ka pauka fisetin hiki ke hōʻeha i ka ʻōpū.

ʻAʻole hiki i ka pauka Fisetin ke loaʻa nā hopena ʻaoʻao akā pili ia me kekahi mau lāʻau lapaʻau, e hopena i ka hoʻololi ʻana i ka metabolism o kēlā mau lāʻau. Ua ʻike ʻia ʻo Fisetin e hoʻemi i ke kiʻekiʻe o ke kō koko i nā ʻano holoholona, he mea maikaʻi loa ia iā ia iho. Akā ke lawe pū ʻia me nā lāʻau lapaʻau anti-diabetic, hiki ke hoʻonui ʻia ka hopena hoʻohaʻahaʻa glucose o nā mea ʻelua, ka mea hoʻohui a me ka lāʻau lapaʻau. Hiki paha kēia i nā pilikia olakino.

Hoʻopili ʻia ka pauka Fisetin e ke akepaʻa, e like me ke ʻano o ka hoʻokaʻawale ʻana o ke koko. Ma muli o kēia, ua manaʻo ʻia e launa pū kēia mau mea ʻelua me ka pauka Fisetin e hoʻonui i nā hopena o nā mea hoʻokahe koko.

ʻO ka pauka Fisetin a me nā mea hoʻohui fisetin ma ka pūnaewele

Hiki ke kūʻai ʻia ka pauka Fisetin ma ka pūnaewele mai nā mea hana pauka fisetin ʻē aʻe, i nā nui e pili ana i ka pono kikoʻī. Hiki ke kōkua ke kūʻai ʻana i ka nui fisetin me ke kumu kūʻai. ʻAʻole ʻokoʻa ke kumukūʻai o Fisetin, a ua like ia me nā mea hoʻohui flavonoid ʻē aʻe.

Ke nānā nei e kūʻai i kahi hoʻohui fisetin, he mea nui e nānā pono i nā mea hana pauka fisetin a me kā lākou hana hana. ʻO kēia ka mea e hōʻoia i ka mālama pono ʻana i nā alakaʻi palekana a me nā protocols hana i ka wā o ka hana ʻana o ka fisetin supplement. He mea koʻikoʻi ke kūʻai ʻana i ka pauka fisetin maʻemaʻe e like me ka hana ʻana no ka mea hoʻohui fisetin maikaʻi loa. Inā ʻaʻole hahai ka mea hoʻolako i nā protocol palekana i ka unuhi ʻana a me ka synthesis o fisetin, hiki ke hoʻohaumia ʻia ka huahana hope a i ʻole nā mea e hōʻino ai i ke olakino kanaka a ʻaʻohe hopena i ke olakino kanaka. Ma kēlā me kēia ʻaoʻao, ʻaʻole ʻike ʻia nā pōmaikaʻi fisetin ʻoiai ka lawe ʻana i ka mea hoʻohui no ka manawa lōʻihi.

He mea nui ka nānā ʻana i nā mea hoʻohui o ka pauka fisetin e kūʻai ʻia ana a me ka ratio hoʻopaʻa ʻana o kēia mau mea e hōʻoia i ke kūʻai ʻia ʻana o ka pauka fisetin maʻemaʻe. Inā ʻaʻole i hana ʻia kēia ʻokoʻa, a laila nui ka nui o ka hoʻonui ʻana i nā hopena ʻaoʻao fisetin a / a i ʻole nā pōmaikaʻi fisetin i hoʻemi ʻia, holoʻokoʻa.