Alzheimer ka maʻi

He aha ka maʻi ʻo Alzheimer?

ʻO ka maʻi o Alzheimer kekahi o nā kumu maʻamau o ke kīnā o ka poʻe ʻelemakule. He maʻi neurological ia e neʻe iki i ka shrinkage o nā lolo a me ka hoʻohaʻahaʻa neuronal mua. ʻO ia nō hoʻi ke ʻano maʻamau o ke dementia, e hopena ana i nā disfunction i ka hoʻomanaʻo, nā mākau pili kaiapili, ka noʻonoʻo, a me ka lawena. Ma ke ao holoʻokoʻa, ʻoi aku ma mua o 30 miliona mau kānaka ma luna o 65 mau makahiki i loaʻa i ka maʻi Alzheimer.
ʻO nā mea maʻi e loaʻa ana i ka maʻi ʻo Alzheimer e hōʻike mua i nā hōʻailona o ka hoʻomanaʻo maikaʻi ʻole e like me ka hiki ʻole ke hoʻomanaʻo i nā hanana hou. Me ka holomua o ka maʻi, hiki i ka maʻi ʻo Alzheimer ke hōʻino i ka hoʻomanaʻo. ʻO ka hopena, ʻaʻole hiki i ka mea maʻi ke hoʻokō i nā hana maʻamau o ke ola o kēlā me kēia lā e like me ka lole iā lākou iho, ka ʻai ʻana, ka ninini ʻana i ko lākou ʻōpū, a pēlā aku.

He aha ke kumu etiology o ka maʻi ʻo Alzheimer?

ʻAʻole maopopo maopopo ke ʻano o ke ʻano etiology no ka maʻi ʻo Alzheimer. Akā, ʻo ka hapa nui o ka poʻe loea i kēia kahua ke manaʻoʻiʻo ʻo ka hana ʻino i loko o nā protein o ka lolo ke kuleana no ke kaulahao o nā hanana e make ai nā neurons a hoʻopau i ka hana o ka lolo. Hōʻike nā noiʻi e loaʻa i ka maʻi ʻo Alzheimer kahi etiology multifactorial, me nā gen, ka nohona, a me ke kaiapuni e kōkua i ka ulu ʻana o ka maʻi Alzheimer.
I nā hihia maʻamau, hiki i kahi mutation genetic ke kanaka i maʻalahi i ka hoʻomohala ʻana iā Alzheimer. I loko o ia mau hihia i hoʻololi ʻia, ua hoʻomaka ka hoʻomaka o nā ʻōuli a ʻoi aku ka wikiwiki o ka holomua.
ʻO ka maʻamau, hoʻomaka ka maʻi ma ka ʻāpana o ka lolo kahi i hoʻokumu ʻia ai ka hoʻomanaʻo. Akā, hoʻomaka ka hana maʻi maoli ma mua o ka hoʻomohala ʻana o nā hōʻailona. I ka pae kiʻekiʻe o ka maʻi, lilo ka lolo i ke ʻano atrophied. ʻO ka mea nui, ua hoʻopili ʻia nā protein ʻelua i ka maʻi o Alzheimer, nā protein Beta-amyloid, a me nā protein Tau.

Poliki

ʻO ka beta-amyloid kahi protein protein kumu i hiki ke lilo i mea ʻona i nā neurons inā hoʻopili lākou i ka lolo. Hiki i nā huhui o nā ʻāpana beta-amyloid ke hoʻopilikia i ke kaʻina hana o ke kamaʻilio ʻana ma waena o nā hunaola. Ke hui pili like kēia mau puʻupuʻu, no ke aha e hana ai i kahi hanana nui i kapa ʻia ʻo amyloid plaques.

Kaulana

No ka hana pono ʻana o nā neurons, hoʻohui ʻia nā protein tau e lawe i nā meaʻai a me nā mea koʻikoʻi e kākoʻo i loko o nā neurons. Ke hoʻonohonoho hou ʻia nā protein tau i nā kuʻi i kapa ʻia ʻo neurofibrillary tangles, hiki iā lākou ke hopena i ka maʻi o Alzheimer. Hiki i kēia mau kuʻekuʻe ke hoʻopilikia i ka lawe ʻana i nā meaʻai i nā neurons, ka hopena o ko lākou make.

Nā Kūlana Pilikino o ka maʻi Alzheimer

Nui a hewahewa nā kumu i hiki ke hoʻonui i kou makaʻu no ka maʻi o Alzheimer, i helu ʻia ma lalo.

makahiki

ʻO ka makahiki kiʻekiʻe ka mea koʻikoʻi koʻikoʻi no ka ulu ʻana o ka dementia, me ka maʻi o Alzheimer. Eia naʻe, ʻaʻole hōʻailona ʻo Alzheimer o ka ʻelemakule a ʻaʻole ia he ʻike maʻamau.

Nā Genetics

Inā ua ʻike mua ʻia kekahi lālā pili o kou ʻohana me Alzheimer, ʻoi aku ka nui o nā makaʻu o Alzheimer ma mua o ka heluna lehulehu.

Down syndrome

ʻO nā mea maʻi i hānau ʻia me Down Syndrome, kahi maʻi chromosomal, maʻalahi i ka hoʻomohala ʻana i ka maʻi ʻo Alzheimer i ka wā ʻōpio. ʻO ka maʻamau, hoʻomohala lākou iā Alzheimer i nā makahiki he ʻekahi a ʻelua paha o ke ola.

ʻO ka hōʻeuʻeu Traumatic Brain

Hiki i ka moʻaukala o ke poʻo poʻo ʻeha ke hoʻonui i kou makaʻu i ka hoʻomohala ʻana i ka maʻi o Alzheimer. Ua hōʻike ʻia nā noiʻi ua hoʻonui ʻia ka hanana o Alzheimer i ka poʻe me kahi hanana o ka ʻehaʻeha o ka lolo traumatic.

ʻAkohola inu wai

Hiki i ka inu ʻona ke hoʻololi mau i ka lolo. Ua hōʻike nā haʻawina nui e pili ana ka hoʻohana ʻana i ka waiʻona me ka dementia.

Kanikani'āʻula.

ʻO nā maʻi hiamoe, e like me ka hiamoe ʻole, pili pū ʻia me ka hoʻonui ʻia o nā hihia o Alzheimer i nā noiʻi nui.

Aloha Hawaii

ʻO nā kumu pilikia no nā maʻi maʻi maʻi coronary e like me ka momona, hypertension, cholesterol kiʻekiʻe, puhi, a diabetes ua pili pū i ka maʻi o Alzheimer.

Nā ʻōuli a me nā hōʻailona

ʻO ka ʻike maʻamau ʻo ka hōʻailona nui o ka maʻi Alzheimer ʻo ia ka nalowale hoʻomanaʻo. I ka wā mua o ka maʻi, pilikia nā maʻi i ka hoʻomanaʻo ʻana i nā hoʻomanaʻo a me nā hanana hou. Me ka holomua o ka maʻi, nā pilikia me ka hāʻule o ka hoʻomanaʻo a me ka naʻau.
Kū ka manaʻo kānalua no ka dementia mai nā hoaaloha pili a i ʻole nā ​​lālā o ka ʻohana ke ulu a lawa nā hōʻailona a lilo i mea ʻike ʻia. Hoʻololi nā pathological i nā mea lolo i ka maʻi e like me kēia.

Nā pilikia hoʻomanaʻo

Ke kaumaha nei ka nalo ʻana o ka hoʻomanaʻo me ka maʻi ʻo Alzheimer, pilikia ka poʻe me ka kamaʻilio o kēlā me kēia lā e like me ka hoʻopoina ʻana i nā kamaʻilio ʻana, ke kuhi hewa ʻana i nā mea pinepine, nalowale i nā wahi kamaʻāina, a me nā pilikia me nā inoa inoa a i ʻole ka manaʻo manaʻo.

Hoololi Pilikino

Hiki iā Alzheimer ke hoʻololi loa i ka pilikino a me ka lawena o ke kanaka. Hiki ke loli i kahi ʻano leʻaleʻa ma mua i kahi maʻi depressive ʻoiai ke hōʻike nei i ka nele o ke aloha ʻole, ka loli o ka naʻau, a me ka haʻalele ʻana i ka nohona.

Ka paʻakikī e hoʻoholo ana

He paʻakikī nā mea maʻi me Alzheimer i ka hoʻoholo ʻana i nā hoʻoholo maikaʻi. No ka laʻana, hana paha ka mea maʻi ma waho o ke ʻano no nā loina kaiaulu e like me ka hele ʻana i ka ua a ʻakaʻaka paha i ka wā hoʻolewa.

Nā paʻakikī me nā hana kamaʻāina

Hiki iā Alzheimer ke hoʻohaunaele i ka hiki i ke kanaka ke hana i nā hana kamaʻāina e like me ke kuke ʻana, ke kaʻa ʻana, ke pāʻani ʻana i nā pāʻani, a pēlā aku. Ke holo nei ka maʻi, hiki i ka mea maʻi ke lilo i ka hiki ke hana i nā hana o kēlā me kēia lā e like me ke kāʻei ʻana iā lākou iho a hoʻoweliweli paha i ko lākou kūlohelohe.

Nā pilikia me ka noʻonoʻo

He paʻakikī loa ka noʻonoʻo a me nā manaʻo no ka poʻe me ka maʻi Alzheimer ma muli o nā pilikia me ka noʻonoʻo. He pilikia paha nā mea maʻi i ka hana ʻana i nā hana he nui i ka manawa like. ʻO nā hana i kēlā me kēia lā e pono ai ke ola e like me ka hoʻokele kālā he mea hiki ʻole ke hana i nā poʻe maʻi me Alzheimer.

Pehea e kuhikuhi ʻia ai ka maʻi ʻo Alzheimer?

Hoʻomaopopo ka hapa nui o nā mea maʻi e pili ana i kā lākou mau hōʻailona e kekahi hoaaloha a ʻohana paha, a ma hope e ʻimi pinepine ka mea maʻi i ka lāʻau. Pono e hana i nā hoʻokolohua hou e hōʻoia i ka ʻike o Alzheimer. Hiki paha i kēia mau hoʻāʻo ke loiloi i ka hoʻomanaʻo o ka mea hoʻomanawanui a me nā mākau ʻike, a me nā hoʻokolohua kiʻi ʻē aʻe. Pono pono nā hoʻokolohua kiʻi ʻana a me nā keʻena hoʻokolohua e kāpae i nā diagnoses ʻokoʻa no ka Alzheimer. Eia nō naʻe, he hōʻoia hōʻoia o Alzheimer ka mea maʻa mau ma hope o ka make ʻana o ka mea maʻi ma ke ʻano he hōʻike histopathological o ka lolo i hōʻike i nā loli e like me nā neurofibrillary tangles a me nā amyloid plaques.

• Nānā Kino: I mea e hoʻoholo ai i nā kumu ʻē aʻe o ka dementia, e nānā ke kauka i kāu reflexes, gait, ikaika a me ka leo, nā hana aʻalolo cranial, ke kaulike, a me ka hoʻonohonoho ʻana.
• Nā noiʻi Laboratory: ʻOiai ʻaʻole hiki i nā hoʻāʻo koko ke hōʻoia i ka hōʻoia ʻana o Alzheimer, pono lākou e kāpae i nā maʻi, nā ʻōpū, a me nā hemahema o ka huaora, ʻo ia mau mea a pau e hopena i nā hōʻailona like me ka Alzheimer. I kekahi mau hihia maʻamau, hiki ke hana ʻia kahi loiloi o ka wai cerebrospinal.
• ʻO ka hoʻāʻo ʻana i ka neurological: ʻo ka nānā ʻana i ke kūlana noʻonoʻo e pili ana i ka loiloi o nā mākau noʻonoʻo, hoʻomanaʻo, a me ka ʻike. Hoʻohālikelike ka hoʻāʻo i ka hiki ke hana i nā hana cognitive a me ka hoʻomanaʻo maʻalahi me nā poʻe ʻē aʻe o nā makahiki like ʻole me nā kūlana pathological.
• Nā haʻawina kiʻi: ʻO ka nānā ʻana i ka lolo me MRI a i ʻole CT ke kī i ka hana ʻana i kahi hōʻailona o Alzheimer. Hiki i kēia mau haʻawina kiʻi ke kōkua i ka ʻike ʻana i nā kumu ʻē aʻe o ka hoʻololi ʻana i nā kūlana noʻonoʻo e like me ka ischemic stroke, hemorrhage, tumors, a i ʻole trauma. Hiki ke ʻike ʻia ka emi ʻana o ka lolo a me nā wahi o ka metabolism dysfunctional ma o nā haʻawina kiʻi. Ke noiʻi ʻia nei nā ʻano hana kiʻi hou e hoʻohana ana i ka PET scan, amyloid PET imaging, a me Tau PET imaging no kā lākou kuleana i ka ʻike ʻana i ka maʻi Alzheimer.
• Plasma Aβ: ʻO Plasma Aβ kahi hoʻāʻo koko i hoʻohana ʻia no ka hoʻoikaika hou ʻana i ka maʻi o Alzheimer. He hōʻoia hōʻoia hou ia ma US a loaʻa i kēia manawa.
• Nā Ho'āʻo Genetic: ʻOiai ʻaʻole i hāʻule ka hoʻāʻo ʻana i ka genetic ma lalo o ka loiloi maʻamau no Alzheimer's, hiki i ka poʻe me nā ʻohana mua i loaʻa i ka maʻi Alzheimer ke hana i nā hoʻokolohua genetic.

He aha nā pilikia o Alzheimer?

ʻO nā pilikia e pili ana i ka maʻi Alzheimer e like me ka hōʻike hōʻikeʻike. ʻO nā pilikia me ka hoʻomanaʻo, ka ʻōlelo, a me ka hoʻokolokolo hiki ke hoʻopili i ke ola o ka mea maʻi a hiki i ka hopena i ko lākou hiki ke ʻimi a loaʻa ka lāʻau. ʻO ka hiki ʻole ke kamaʻilio i ka ʻeha, nā ʻōuli, a me ka ukali ʻana i ka mālama ʻana e hōʻeha pū paha i ka papa maʻi.
I nā pae hope loa o ka maʻi, hiki i ka atrophy o ka lolo a me nā loli ke hoʻololi i ka hana maʻamau. Hiki i ka mea hoʻomanawanui ke lilo i ka hiki ke kaohi i ka ʻōpū a me ka neʻe ʻana o ka puhū, a he pilikia pū paha me ka ale ʻana. ʻO nā pilikia hou e pili ana i nā maʻi concomitant, kahi hoʻonui i nā hanana o ka hāʻule, malnutrisi, make wai, a me nā hoʻololi o ka ʻōpū.

Hiki ke pale ʻia ka maʻi Alzheimer?

Minamina, hōʻike nā hōʻike o kēia manawa ʻaʻole hiki ke pale aku i ka maʻi ʻo Alzheimer. Akā, e hōʻalo ana i nā kumu pilikia e pili ana me Alzheimer he mea pono paha e hoʻololi i ka papa maʻi a hoʻemi i ka likelike o ka ʻeha ʻana mai Alzheimer me ka hoʻonui ʻana o ka makahiki. Ma ka hoʻomaʻamaʻa ʻana i kahi nohona olakino e like me ka hoʻoikaika kino ʻana i kēlā me kēia lā, ka ʻai ʻana i ka papaʻai me nā mea kanu a me nā huaʻai, ka nānā ʻana i ke olakino maʻamau, ka mālama ʻana i ke kahe o ke koko a me nā pae kolesterol i ka mālama ʻana, ka hōʻalo ʻana i nā mea hana leʻaleʻa e like me ka wai ʻona a i ʻole mau paka paha e kōkua i ka mālama ʻana i ka hoʻomanaʻo a me ka hana noʻonoʻo. hope ma ke ola. Eia kekahi, ke komo ʻana i nā hana e koi ai i ka noʻonoʻo a me ke komo ʻana o nā hana noʻonoʻo kiʻekiʻe e like me ka pāʻani ʻana i ka chess, ka hoʻoponopono ʻana i nā pilikia o ka makemakika, a i ʻole ke pāʻani ʻana i nā pāʻani paʻakikī hiki ke kōkua i ka mālama ʻana i nā hana noʻonoʻo me ka hoʻonui ʻana o ka makahiki.

Ka mālama ʻana i ka maʻi Alzheimer

Hoʻohana ʻia nā lāʻau i kēia manawa e mālama i ke kōkua o Alzheimer me nā ʻōuli. ʻAʻole lākou e hoʻololi i ka papa maʻi a hoʻōla paha i ke ʻano. ʻO ka mea nui, ʻelua mau ʻano lāʻau i kuhikuhi ʻia i kēia manawa no Alzheimer.

Nā mea kūpale Cholinesterase

I ka maʻi o Alzheimer, aia ka emi ʻana o ka acetylcholine, kahi neurotransmitter, i hoʻopili ʻia i ka papa maʻi. No laila, hiki ke kōkua ʻia ka pāpā ʻana i nā enzyme e wāwahi i ka acetylcholine i ka mālama ʻana iā Alzheimer.
Hoʻonui nā mea kūpale Cholinesterase i nā pae o ka neurotransmitter, Acetylcholine e ka pāpā ʻana i kona haki. ʻO lākou ka lāʻau mua o ke koho i nā maʻi āpau i ʻike hou ʻia me ka maʻi Alzheimer a hiki ke hoʻomaikaʻi kūpono i nā ʻōuli. ʻO nā mea pāpālina cholinesterase maʻamau i hoʻohana ʻia i ka mālama ʻana i ka maʻi o Alzheimer he galantamine, rivastigmine, a me donepezil.

ʻO ka mea hoʻokūkū receptor NMDA

Memantine, hoʻohana ʻia kahi antagonist receptor NMDA i ka mālama ʻana i ka maʻi o Alzheimer. Hoʻohana kūikawā ʻia ia i kēlā mau maʻi ʻaʻole hiki ke hoʻomanawanui i ka mālama ʻana me nā mea hoʻopā Cholinesterase. Loaʻa ka hoʻomaikaʻi kūpono i nā hōʻailona ke mālama ʻia me memantine. ʻOiai ʻo ka mālama pū ʻana o memantine me nā mea kāohi cholinesterase ʻē aʻe i hōʻike ʻole ʻia he maikaʻi, ke mālama ʻia nei nā noiʻi e nānā i nā pono kūpono.

He lāʻau'ē aʻe

Hoʻohana ʻia ka nui o nā huaora, nā mea hoʻohui, a me nā mea kanu i nā poʻe maʻi me ka maʻi o Alzheimer no ka mea e pono ai lākou no ka hoʻomaikaʻi ʻana i ka hana cognitive. ʻAʻole maopopo nā haʻawina e loiloi ana i nā pono o kēia mau lāʻau. ʻO kekahi mau lāʻau lapaʻau ʻē aʻe i loaʻa nā hopena maikaʻi:

9-Me-BC Pauka

9-ME-β-Carbolines he hui pū pyridoindole, i loaʻa mai nā ala endogenous a me exogenous. Ua loaʻa i ka noiʻi ma 9-ME-β-Carbolines hiki i kēia mau mea hoʻohui ke hana i nā hopena maikaʻi e like me neuroprotection, neurostimulation, anti-inflammatory action, a me neuroregeneration. Eia kekahi, ua kāohi ʻo 9-ME-BC i ka hoʻolaha ʻana o nā neurons dopaminergic me ka ʻole e hoʻopili i ka lawe ʻia ʻana o ka dopamine. Hōʻike ʻo 9-ME-BC i nā hana anti-proliferative me nā hopena ʻawahia liʻiliʻi i nā neurons.
Hana ʻia nā hana a 9-ME-BC e ka transporter cation organic, a hoʻoulu hoʻi i ka hōʻike o nā genes i kuleana no ka synthesist o nā mea neurotrophic pono e like me BDNF, NCAM1, a me TGFB2. Kūpono kēia mau mea neurotrophic no ka ulu ʻana o nā neurites, i hiki ke loaʻa nā pono neurodegenerative a me nā neuroprotective ke hālāwai nā neurons me nā toxins like ʻole. No laila, he nui nā pono o 9-ME-BC ma nā neurons i lilo ia i mea kōkua maikaʻi e kūʻē i nā maʻi neurological e like me ka maʻi Parkinson a me ka maʻi ʻo Alzheimer.

CMS121 Pauka

ʻO CMS121 i loaʻa mai ka fisetin he hui neuroprotective i hāʻawi waha ʻia. ʻO Fisetin kahi pūhui flavonoid i loaʻa mai nā huaʻai a me nā mea kanu. Ua hōʻike nā haʻawina he hopena maikaʻi ka fisetin i ka cognition a me ke kamaʻilio neuronal. Me kona mau waiwai antioxidant, hiki i ka fisetin ke hoʻonui i nā pae o nā mea neuroprotective i loko o ka Central Nervous System. Eia kekahi, loaʻa i ka fisetin nā waiwai anti-inflammatory. ʻO kēia mau pono āpau o fisetin e hōʻike ana he mea pono ia i ka mālama ʻana i nā maʻi i hoʻopilikia ʻia i ka kamaʻilio neuronal a me ka hana.
ʻO ka derivative o ka lawaiʻa, CMS121 ka pauka he 400 mau manawa ke kiʻekiʻe aʻe ma mua o ka fisetin. Ua hōʻike pū kekahi ʻo CMS121 i nā waiwai hou aku e like me ka hoʻomaikaʻi ʻana i ka ʻike pharmacological a me ke kūpaʻa o kona ʻano kino me ka bioavailability oral maikaʻi. Hiki i ka CMS121 ke lilo i mea kōkua i nā mea maʻi me nā maʻi neurological e like me ka maʻi Alzheimer.

CAD31 pauka

Loaʻa iā CAD31 nā hopena maikaʻi he nui i hiki ke hana i ka lohi ʻana i ka hoʻohaʻahaʻa pili makahiki o nā neurons. Ua hōʻike ʻia e hoʻonāukiuki i nā hunaola kūmole i lawe ʻia mai nā embryos kanaka e hana kope. ʻO nā hoʻokolohua e hoʻāʻo i nā pono o CAD31 i kahi hanana maʻi i hana ʻia i loko o nā noiʻi holoholona. ʻO nā mice me nā maʻi ʻo Alzheimer i lawelawe ʻia me CAD31. Ua hoʻomaikaʻi ka noiʻi i ka hoʻomaikaʻi ʻana i nā hana hoʻomanaʻo a me ka hoʻemi ʻana o ka mumuna i nā mice. Ua hoʻoholo ʻia hiki i ka CAD31 ke lilo i neuroprotective a hiki ke hiki keʻaʻa i ka pale o ka lolo-lolo me ka maikaʻi.
Hana ʻo CAD 31 ma o ka hoʻokumu ʻana i nā synapses a me nā pahuhopu metabolic pathways e like me ka metabolism o nā momona momona. ʻO kēia mau noiʻi mua i loaʻa nā ʻōlelo hoʻohiki no ka hoʻohana ʻana o CAD-21 i nā maʻi neurological me ka maʻi ʻo Alzheimer a me nā ʻano like ʻole o ka senile dementia.

Ka lehu o J147

ʻO J147 ka paukū i loaʻa mai iā Curcumin, ka mea ponoʻī mai kahi mea ʻala India i ʻike ʻia he turmeric. He hui pū ʻo Curcumin me nā hopena maikaʻi i ʻike nui ʻia e like me nā anti-inflammatory waiwai, nā hopena antioxidant, hoʻoliʻiliʻi i ka toxine i hoʻokomo ʻia i ka protein protein, a pēlā aku. Minamina, ʻaʻole maikaʻi ka curcumin ponoʻī ʻoiai he bioavailability maikaʻi loa kona a ʻaʻole hiki ke hele i ka pale o ka lolo-koko.
ʻAʻole like me curcumin, ʻo J147 ka paukū kahi i ʻoi aku ka paʻa o ka pilikino pilikino, CNS penetrance maikaʻi, a he bioavailability waha maikaʻi hoʻi. Loaʻa i ka mole J147 ma mua o 10 mau manawa kiʻekiʻe i ka hoʻohālikelike ʻana me curcumin. ʻO nā haʻawina holoholona i mālama ʻia a hiki i kēia manawa ma ka pauma J147 i hōʻike ʻia he mea maikaʻi paha ia i ka heluna ʻelemakule a me nā mea e loaʻa nei i ka maʻi ʻo Alzheimer.

Monosialotetrahexosyl ganglioside Sodium (GM1) pauka

ʻO ka Monosialotetrahexosylganglioside sodium (GM1) kahi mea hoʻohui kaulana i hoʻohana ʻia no ka mālama ʻana i nā maʻi neurological like ʻole. ʻO kēia ka mea nui ma muli o kāna hana neuroprotective. Akā, loaʻa iā ia nā hana pale pono i nā kīʻaha koko e hāʻawi ana i ka CNS. Ma kahi haʻawina i hana ʻia ma ka pūhui GM1, ua ʻike ʻia ʻo GM1 i nā hana pale i nā radical manuahi i hoʻokomo ʻia i nā hōʻeha cell.
ʻO ka neuroprotective, a me nā waiwai antioxidant o Monosialotetrahexosyl ganglioside Sodium (GM1) pauka, hoʻolilo ia i mea kōkua kūpono no nā maʻi he nui o ka ʻōnaehana waena e like me akā ʻaʻole kau palena ʻia i ka maʻi ʻo Alzheimer, maʻi ʻo Parkinson, dementia senile, a pēlā aku.

ʻO ka pauka Octacosanol

ʻO ka Octacosanol kahi hui kemika i loaʻa mai nā mea kanu e like me ka aila germ germ a me ke kō. Structurally a chemically, he waiwai like kona i ka Wikamina E. Ua loaʻa i kekahi mau noiʻi he octacosanol e loaʻa ai ka antioxidant, neuroprotective, a me nā anti-inflammatory. Hoʻohana nui ʻia ia e nā mea pāʻani a hoʻohana ʻia hoʻi ma ke ʻano he mea kōkua i ka mālama ʻana i nā maʻi neurological e like me ka maʻi Parkinson, ka maʻi ʻo Alzheimer, ka maʻi ʻo Lou Gehrig, a me nā mea hou aku.

Ke hoʻomau nei i ka noiʻi ʻana ma ka maʻi ʻo Alzheimer

ʻAʻohe lāʻau lapaʻau no ka maʻi ʻo Alzheimer i kēia manawa, a ʻo nā lāʻau āpau i hoʻohana ʻia i kēia manawa i ka mālama ʻana i ka maʻi o Alzheimer hiki ke hoʻomaikaʻi wale i nā ʻōuli no ka manawa pōkole ma o ka hoʻonui ʻana i ka hana o nā neurotransmitters ma loko o ka ʻōnaehana nūhou waena. Akā ʻaʻole hiki i kēia mau lāʻau ke pale i ka maʻi mai ka holomua.
Nui nā haʻawina e mālama ʻia ana e hoʻomaopopo maikaʻi i ke kumu o ka maʻi etiology a me ka pathophysiology e hoʻomohala i nā lāʻau lapaʻau no Alzheimer. Manaʻo ka poʻe noiʻi ma kēia kahua e ʻimi i nā koho lapaʻau e hiki ke hoʻopanee a hoʻopaʻa paha i ka piʻi ʻana o ka maʻi i kahi pae kiʻekiʻe. Maliʻa paha ʻaʻole pili nā ʻano hana o ka wā e hiki mai ana i ka lāʻau hoʻokahi, akā ʻo ka hui pū ʻana o kekahi mau lāʻau e hana ana ma nā ala he nui.

Ka wānana o ka maʻi o Alzheimer

ʻOiai hoʻohana ʻia kekahi mau lāʻau e mālama ai i ka maʻi o Alzheimer, hiki iā lākou ke hoʻolohi i ka holo ʻana o ka maʻi. Eia nō naʻe, ʻoi aku ka waiwai o kēia mau lāʻau lapaʻau i ko lākou hoʻomaikaʻi ʻana i ka hiki i ka mea maʻi ke kūʻokoʻa a hana i kā lākou mau hana i kēlā me kēia lā me ke kōkua liʻiliʻi. Loaʻa nā lawelawe like ʻole e mālama i nā maʻi me ka maʻi Alzheimer. Minamina, ʻaʻohe lāʻau lapaʻau i ʻike ʻia no ka maʻi o Alzheimer.

Reference:

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